Characterization of hepatitis B virus X gene quasispecies complexity in mono-infection and hepatitis

• 作 者: Cristina Godoy David Tabernero
• 机 构: LiverPathologyUnit,LiverUnit,CentrodeInvestigació,nBiomé,dicaenReddeEnfermedadesHepá,tic
• 出 处: 世界胃肠病学杂志:英文版
• 发表日期: 2019年13期
• 关键词: HEPATITIS B VIRUS HEPATITIS DELTA VIRUS HEPATITIS B X gene Next-generation seque
• 基金项目: Instituto de Salud Carlos III, grants PI15/00856 and PI17/02233,co-financed by the European Regional Development Fund (ERDF).

BACKGROUND Hepatitis delta virus (HDV) seems to strongly suppress hepatitis B virus (HBV) replication, although little is known about the mechanism of this interaction. Both these viruses show a dynamic distribution of mutants, resulting in viral quasispe