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目的探讨舒乐安定的助眠效果以及药物依赖情况。方法选取2012年4月—2014年3月在海口市第四人民医院治疗的失眠症患者124例,随机分为观察组(n=62,给予舒乐安定)和对照组(n=62,给予阿米替林),观察两组疗效以及药物依赖情况,同时采用纽芬兰纪念大学幸福度量表,对两组患者治疗前后进行问卷调查。结果观察组总有效率为93.55%,明显高于对照组的79.03%,差异有统计学意义(P<0.05);观察组和对照组治疗后幸福度总分均较治疗前有所增高,差异有统计学意义(P<0.05);观察组治疗后幸福度总分为(37.18±5.28)分,明显高于对照组的(30.22±4.17)分,差异有统计学意义(P<0.05);观察组有33例产生药物依赖性,占53.23%,而对照组有18例产生药物依赖性,占29.03%,两组差异有统计学意义(P<0.05)。结论舒乐安定片治疗失眠症有较好的疗效,但仍存在药物依赖性的问题。
Objective To investigate the effects of diazepam on sleep-deprivation and drug dependency. Methods 124 patients with insomnia treated in the Fourth People ’s Hospital of Haikou from April 2012 to March 2014 were randomly divided into observation group (n = 62) and control group (n = 62) Amitriptyline). The curative effect and drug dependency of the two groups were observed. At the same time, Questionnaire of Happiness of Newfoundland Memorial University was used to investigate the two groups of patients before and after treatment. Results The total effective rate in the observation group was 93.55%, which was significantly higher than that in the control group (79.03%), the difference was statistically significant (P <0.05). The total score of happiness in observation group and control group after treatment was higher than that before treatment, (37.18 ± 5.28), which was significantly higher than that of the control group (30.22 ± 4.17), the difference was statistically significant (P <0.05). 33 cases in the observation group were drug-dependent, accounting for 53.23%, while 18 cases in the control group were drug-dependent, accounting for 29.03%. The difference between the two groups was statistically significant (P <0.05). Conclusion Shuilean tablets for the treatment of insomnia have a good effect, but there are still drug-dependent problems.