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目的了解慢性胃炎患儿胃固体排空功能。方法对2008年1月至2012年1月首都儿科研究所附属儿童医院6～17岁因反复上腹部(或脐周)疼痛、上腹部不适伴有腹胀、嗳气、恶心、呕吐、早饱等消化道症状持续2个月以上,并且每周至少发作1次的儿童需要做胃镜检查者,进行电子胃镜常规检查,同时取病理活检并进行幽门螺杆菌(HP)检测。对确诊慢性胃炎的65例患儿行钡条胃固体排空试验,计算5h胃排空情况,收集服用钡条后24h的临床症状和体征。结果 HP感染总阳性率为27.7%,5h胃排空异常率HP阳性者占11.1%,HP阴性者占21.3%,两者差异无统计学意义(P>0.05)。HP阳性者无论是否有胃排空异常,其胃黏膜病理中-重度炎症者占66.7%。慢性胃炎患儿5h胃排空率<50%者占18.5%,胃排空率<75%者占23.1%。慢性胃炎患儿服用钡条后24h内均无任何异常症状和体征。结论部分慢性胃炎患儿存在胃动力障碍,临床症状不能完全反映胃固体排空情况。对于6～17岁儿童服用钡条行胃固体排空功能检查安全并符合自然生理状态。HP阳性者中-重度慢性胃炎发生率高。
Objective To understand the gastric emptying function in children with chronic gastritis. Methods From January 2008 to January 2012, the Children’s Hospital affiliated to Capital Institute of Pediatrics, Beijing Children’s Hospital aged 6 to 17 years old suffered from diarrhea, belching, nausea, vomiting and early satiety due to repeated upper abdomen (or umbilical cord) pain, upper abdomen discomfort, Road symptoms persist for more than 2 months, and at least 1 episode per week of children need to do endoscopy, electronic gastroscope routine examination, and pathological biopsy and Helicobacter pylori (HP) test. Sixty-five children diagnosed with chronic gastritis underwent barium-based gastric emptying test. The gastric emptying for 5 hours was calculated and the clinical symptoms and signs were collected 24h after barium administration. Results The total positive rate of HP infection was 27.7%. The abnormal gastric emptying rate at 5h was 11.1% and the negative was HP at 21.3%. There was no significant difference between the two groups (P> 0.05). HP-positive patients with or without abnormal gastric emptying, the gastric mucosal pathology - severe inflammation accounted for 66.7%. Children with chronic gastritis 5h gastric emptying rate <50% accounted for 18.5%, gastric emptying rate <75% accounted for 23.1%. Children with chronic gastritis after taking barium within 24h without any abnormal symptoms and signs. Conclusion Some children with chronic gastritis have gastric motility disorder, and the clinical symptoms can not fully reflect the gastric emptying. For 6 to 17-year-old children taking barium gastric emptying function check safety and in line with the natural state. HP-positive in - high incidence of chronic gastritis.