论文部分内容阅读
目的：研究静脉注射（静注）硫酸镁对冠心病左室舒张功能的影响。方法：冠心病病人６４例，治疗组３４例（男性１９例，年龄６４ａ±ｓ１０ａ，女性１５例，年龄６６ａ±１０ａ），于５ｍｉｎ内缓慢静注经稀释的硫酸镁２ｇ；对照组３０例（男性２０例，年龄６６ａ±１０ａ，女性１０例，年龄６５ａ±９ａ），于５ｍｉｎ内静注０．９％氯化钠注射液２０ｍＬ。结果：静注硫酸镁后舒张早期最大流速（Ｅ波峰值），Ｅ／Ａ峰值比值，舒张早期血流速度时间积分（Ｅ波积分），Ｅ／Ａ积分比值，舒张早期快速充盈减速斜率（Ｅ波减速斜率），Ａ＿Ａｒ间期等参数较用药前均显著增大，Ｐ＜０．０５或Ｐ＜０．０１；而对照组无显著变化。结论：静注硫酸镁能改善冠心病左室舒张早期和舒张晚期的功能。
Objective: To study the effect of intravenous (intravenous) magnesium sulfate on left ventricular diastolic function in patients with coronary heart disease. Methods: Sixty-four patients with coronary heart disease were enrolled in the study. The treatment group consisted of 34 patients (19 males, 64a ± s10a, 15 females, 66a ± 10a) 20 males, age 66a ± 10a, 10 females, age 65a ± 9a), within 5min intravenous injection of 0.9% sodium chloride injection 20mL. Results: The maximal early diastolic velocity (E wave peak), E / A peak ratio, early diastolic blood flow velocity time integral (E wave integral), E / A integral ratio, early diastolic filling deceleration slope Wave deceleration slope), A_Ar interval and other parameters were significantly increased compared with before treatment, P <0.05 or P <0.01; while the control group had no significant change. Conclusion: Intravenous magnesium sulfate can improve left ventricular diastolic function and early diastolic function in patients with coronary heart disease.