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目的探讨原发性甲状旁腺功能亢进症(PHPT)患者合并甲状腺疾病的临床特征。方法回顾性分析29例手术治疗并经病理检查确诊的PHPT患者的临床资料。结果29例PHPT患者中,无甲状腺疾病组14例,合并甲状腺疾病组15例(51.7%)。其中,甲状腺良性病变10例(结节性甲状腺肿9例,桥本氏甲状腺炎1例),恶性病变5例(甲状腺乳头状癌4例,甲状腺隐匿性癌1例)。合并甲状腺疾病组的平均年龄大于无甲状腺疾病组(P<0.05)。结论 PHPT患者合并甲状腺疾病的发病率高,且甲状腺恶性病变较多。
Objective To investigate the clinical features of patients with primary hyperparathyroidism (PHPT) complicated with thyroid disease. Methods The clinical data of 29 patients with PHPT diagnosed by pathology were retrospectively analyzed. Results Of the 29 PHPT patients, 14 had no thyroid disease and 15 had thyroid disease (51.7%). Among them, benign thyroid lesions in 10 cases (nodular goiter in 9 cases, Hashimoto’s thyroiditis in 1 case), 5 cases of malignant lesions (thyroid papillary carcinoma in 4 cases, thyroid occult carcinoma in 1 case). The mean age of patients with thyroid disease was higher than those without thyroid disease (P <0.05). Conclusion PHPT patients with high incidence of thyroid disease, and thyroid malignant lesions more.