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目的：了解偏头痛患者丘脑血流的变化。方法：用９９ｍＴｃ－六甲基两二胺肟和Ｎｏｖｏ－８１０高分辨率ＳＰＥＣＴ仪，以感兴趣区（ＲＯＩ）相对放射性计数百分率（ＲＯＩ％）为指标，对６０例次偏头痛患者的丘脑血流变化作了定量分析。结果：与无预兆偏头痛组的平均ＲＯＩ％值（２４９．Ｉｆ１４．９）相比，预兆偏头痛组ＲＯＩ％升高（２５９．１±１７．１），差异有显著意义（Ｐ＜０．０５）；偏瘫、偏身感觉异常预兆偏头痛组升高更明显（２６３．８±１７．２），差异有极显著性（Ｐ＜０．０１）；而单纯视觉预兆组稍升高（２５５．１±１６．４），差异无显著意义（Ｐ＞０．０５）。结论：偏瘫、偏身感觉异常预兆组丘脑血流升高，原因可能为：①缺血后高灌注。②除丘脑外，其它脑区血流减少。③各种神经、化学性刺激的结果。
Objective: To understand the changes of thalamic blood flow in migraineurs. Methods: Using 99mTc-hexamethyldiamine oxime and Novo-810 high-resolution SPECT instrument, the relative radioactivity count (ROI%) of ROI as index, Flow changes were quantitatively analyzed. Results: Compared with the mean ROI% (249.If14.9) in the migraine without migraine group, the ROI% in migraine with migraine was significantly higher (259.1 ± 17.1) (P <0. 05). Hemiplegia and hemifacial hyperalgesia were more obvious in migraine group (263.8 ± 17.2), with significant difference (P <0.01) .1 ± 16.4), no significant difference (P> 0.05). Conclusion: Hemiplegia, hemifacial hyperalgesia induced by hypothalamic hypothalamic blood flow may be due to: ① high perfusion after ischemia. ② In addition to the thalamus, other brain areas reduce blood flow. ③ various neurological, chemical stimulation results.