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目的:探讨暴露性复合外伤病人凝血功能检查中的各参数与GCS和ISS评分间的关系。方法:收集60例复合外伤病人(男:51例;女:9例)临床资料,按软组织外伤,颅脑外伤,颅脑外伤合并其他复合外伤以及复合外伤分组,分别测定病患PLT,APTT,INR,AT,PAI-1,FDP,DD,FIB水平分析不同组间差异。结果:ISS与INR,APTT,DD,FDP,AT,FIB之间差别具有统计学意义(P<0.05);C组和其他组在INR,DD,FIB,APTT,AT参数上差别具有统计学意义(P<0.05);是否是颅脑外伤和INR,DD,FIB参数具有统计学意义(P<0.05)。结论:颅脑外伤病人的凝血功能参数异常,颅脑外伤合并其他外伤病人存在更多凝血功能参数异常。关注这些凝血参数,对于治疗效果的前瞻性预测和早期阶段凝血功能异常发生的原因判断都是十分必要。
Objective: To investigate the relationship between the parameters of coagulation test and GCS and ISS scores in patients with exposed composite trauma. Methods: The clinical data of 60 patients with combined trauma (male: 51, female: 9) were collected. According to the soft tissue trauma, craniocerebral trauma, craniocerebral trauma combined with other trauma and compound trauma, the PLT, APTT, INR, AT, PAI-1, FDP, DD, FIB levels were analyzed for differences between groups. Results: The difference between ISS and INR, APTT, DD, FDP, AT, FIB was statistically significant (P <0.05). There was significant difference in INR, DD, FIB, APTT and AT between C group and other groups (P <0.05); whether craniocerebral trauma and INR, DD, FIB parameters were statistically significant (P <0.05). Conclusion: There are abnormal coagulation parameters in patients with craniocerebral trauma and more coagulation dysfunction parameters in patients with traumatic brain injury and other traumatic injuries. Concerned about these coagulation parameters, for the prospective prognosis of treatment and early stage coagulation disorders occur because of the reasons are very necessary.