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目的:评估经阴道四维子宫输卵管超声造影技术(4D-SonoVue-HyCoSy)对不孕症患者的舒适程度及诊断输卵管通畅性的准确度。方法:对655名不孕女性患者行4D-S-HyCoSy,观察患者术中疼痛程度、副反应及术后并发症;以腹腔镜下美兰通液检查的22例为对照,比较其诊断输卵管通畅性的准确度。结果:68.55%患者无明显术中疼痛,19.54%轻度疼痛,9.92%中等疼痛,1.53%重度疼痛。1.98%有轻微迷走神经反应。4D-SHyCoSy诊断输卵管通畅的准确率为90.9%,敏感度90.9%,特异度90.9%,阳性预测值76.9%,阴性预测值96.8%,与腹腔镜检查无明显差异(P=0.625)。结论:采用4D-S-HyCoSy评估输卵管通畅性安全、有效、快捷、准确。
Objective: To assess the accuracy of transvaginal 4D SonoVue-HyCoSy in patients with infertility and the diagnostic accuracy of tubal patency. Methods: We performed 4D-S-HyCoSy on 655 infertile women and observed intraoperative pain degree, side effects and postoperative complications. Twenty-two patients underwent laparoscopic treatment with Meilantong solution were compared. The diagnosis of fallopian tube Unobstructed accuracy. Results: 68.55% patients had no obvious intraoperative pain, 19.54% mild pain, 9.92% moderate pain, and 1.53% severe pain. 1.98% had slight vagal reaction. The diagnostic accuracy of 4D-SHyCoSy was 90.9%, the sensitivity was 90.9%, the specificity was 90.9%, the positive predictive value was 76.9% and the negative predictive value was 96.8%. There was no significant difference between 4D-SHyCoSy and laparoscopy (P = 0.625). Conclusion: The 4D-S-HyCoSy assessment of tubal patency is safe, effective, rapid and accurate.