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本文报告秋水仙碱治疗四氯化碳所致大白鼠慢性肝损害的胶原纤维和肝细胞酶活性、糖原和核糖核酸量的变化。所试动物以组织化学和组织学方法进行观察。结果提示秋水仙碱有抑制慢性肝损害胶原纤维形成的作用,但对肝细胞功能的恢复作用不明显。
This article reports on the changes of collagen fibers and hepatic cell enzyme activity, glycogen and ribonucleic acid levels in chronic liver damage caused by colchicine treatment of carbon tetrachloride in rats. The animals tested were observed by histochemical and histological methods. The results suggest that colchicine can inhibit the formation of collagen fibers in chronic liver damage, but the recovery of hepatocyte function is not obvious.