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目的:探讨骨化三醇冲击治疗尿毒症继发性甲状旁腺功能亢进的临床疗效。方法:选取84例尿毒症继发性甲状旁腺功能亢进患者作为本次的研究对象,以治疗方式的不同将所有患者分为观察组和对照组,每组42例,对照组行骨化三醇常规治疗,观察组患者行骨化三醇冲击治疗,治疗后比较两组患者的临床疗效及血清钙(Ca)、磷(P)和甲状旁腺激素(PTH)指标情况。结果:两组患者临床疗效及血清Ca、P及PTH比较均有明显统计学意义(p<0.05)。结论:给予尿毒症继发性甲状旁腺功能亢进患者骨化三醇冲击治疗可取得良好的治疗效果,临床价值较高,可推广应用。
Objective: To investigate the clinical effect of calcitriol treatment on secondary hyperparathyroidism of uremia. Methods: Eighty-four patients with secondary hyperparathyroidism of uremia were selected as the object of study. All patients were divided into observation group and control group according to different treatment methods. Each group included 42 patients, The patients in the observation group were treated with calcitriol shock therapy. The clinical efficacy, serum calcium (Ca), phosphorus (P) and parathyroid hormone (PTH) were compared between the two groups after treatment. Results: The clinical curative effect and serum Ca, P and PTH in both groups were statistically significant (p <0.05). Conclusion: The treatment of calcitriol in patients with secondary hyperparathyroidism of uremia may achieve a good therapeutic effect, which is of high clinical value and can be popularized and applied.