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[目的]探讨老年食管癌适形放疗的疗效及放射性损伤。[方法]收集并分析行根治性三维适形放疗的40例老年食管癌患者,观察近期及远期疗效,及肺脏、心脏的不良反应。[结果]38例患者完成放疗,完全缓解19例(50%),部分缓解17例(44.7%),无缓解2例(5.3%),总有效率为94.7%。全组患者1、3年局部控制率分别为85.9%、58.7%,1、3年生存率分别为76.3%、42.1%。全组患者≥Ⅱ级急性放射性肺炎的发生率为30%,但食管癌放疗对心脏无显著影响。[结论]老年食管癌患者采用适形放疗,能取得较好的近期及远期疗效,放射性损伤在可接受范围内。
[Objective] To investigate the efficacy and radiation injury of conformal radiotherapy for senile esophageal cancer. [Methods] Forty elderly patients with esophageal cancer who underwent radical three-dimensional conformal radiotherapy were collected and analyzed. The short-term and long-term effects, and lung and heart adverse reactions were observed. [Result] The complete radiotherapy was completed in 38 patients. Complete remission was achieved in 19 cases (50%), partial remission in 17 cases (44.7%) and no remission in 2 cases (5.3%). The total effective rate was 94.7%. The overall control rates of the patients in one and three years were 85.9% and 58.7% respectively, and the 1 and 3-year survival rates were 76.3% and 42.1% respectively. The incidence of ≥ Ⅱ grade acute radiation pneumonitis in all the patients was 30%. However, radiotherapy of esophageal cancer had no significant effect on the heart. [Conclusion] The elderly patients with esophageal cancer using conformal radiotherapy, can achieve better short-term and long-term efficacy, radiation damage within the acceptable range.