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Krill和Klien(1965)曾将家族性玻璃疣、黄色斑点状眼底和白点状眼底归为单一名称“斑点状眼底综合症”(flecked retina Syndrome,FRS)。通常这三种病都有白色或淡黄色“斑点”眼底损害。他们强调在视网膜电流图(ERG),眼电图(EOG)和暗适应研究有类似发现。因为异常的EOG只是常在明显地视网膜色素上皮受累的弥散性疾患见到,所以Krill和Klien结论:组成斑点状眼底综合症的这些病的基本缺陷是在视网膜色素上皮细胞,他们推论,真正的病理表现要比眼底镜所看到的广泛得多。 Farkas等证明组织学与电生理表现支持Krill等的信念,即在家族性玻璃疣病中出现视
Krill and Klien (1965) once classified familial drusen, yellow speckled fundus and white dotted fundus as the single name flecked retina syndrome (FRS). Usually these three diseases have white or light yellow “spots” fundus damage. They emphasized that similar findings were found in retinal electrogram (ERG), electro-oculography (EOG), and dark adaptation studies. Since abnormal EOG is seen only often in diffuse disorders that apparently involve retinal pigment epithelium, Krill and Klien concluded that the basic defect in these conditions that make up the specular fundus syndrome is in retinal pigment epithelium, and they infer that the true The pathological findings are much broader than those seen with ophthalmoscopes. Farkas et al. Demonstrated that histology and electrophysiological performance support the belief of Krill et al. That visualization in familial drusen