Circadian misalignment on submarines and other non-24-h environments-from research to application

• 作 者: Jin-Hu Guo Xiao-Hong Ma Huan Ma Yin Zhang Zhi-Qiang Tian Xin Wang Yong-Cong Shao
• 机 构: Key Laboratory of Gene Engineering of the Ministry of Education,State Key Laboratory of Biocontrol,S
• 出 处: 军事医学研究（英文版）
• 发表日期: 2021年1期
• 关键词: Circadian rhythm Circadian clock Entrainment range Metabolism Alertness Submarin

Circadian clocks have important physiological and behavioral functions in humans and other organisms,which enable organisms to anticipate and respond to periodic environmental changes.Disturbances in circadian rhythms impair sleep,metabolism,and behavior.People with jet lag,night workers and shift workers are vulnerable to circadian misalignment.In addition,non-24-h cycles influence circadian rhythms and cause misalignment and disorders in different species,since these periods are beyond the entrainment ranges.In certain special conditions,e.g.,on submarines and commercial ships,non-24-h watch schedules are often employed,which have also been demonstrated to be deleterious to circadian rhythms.Personnel working under such conditions suffer from circadian misalignment with their on-watch hours,leading to increased health risks and decreased cognitive performance.In this review,we summarize the research progress and knowledge concerning circadian rhythms on submarines and other environments in which non-24-h watch schedules are employed.