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Kopsamine(I): Mr=456.50, orthorhombic, P212121, a=ll.245(3), b=12.547(2), c=15.043(3)A, Z=4, Dc=1.429g.cm-3, V=2122.5A3, final R=0.041 for 2008 observed reflections.N-carbomethoxy-11-methoxy-12-hydroxy-kopsinaline(Ⅱ): Mr=458.52, mono-clinic, P21,a=8.424(2), b=13.037(1), c=9.883(1)A,β=90.14(2)°, Z=2, Dc= 1.403g·cm-3, V=1085.4 A3, final R=0.039 for 1687 observed reflections.In the structures: The rings A,B and E(I) take envelop conformations. The ring C takes chair conformation and the ring D boat conformation. There are intramolecular hydrogen bonds 0(5)-HO(5)...0(1) both in molecule(I) and molecule(Ⅱ), which formed the distorted seven-membered ring with atoms C(22), N(1), C(2), and C(18).
Kopsamine (I): Mr = 456.50, orthorhombic, P212121, a = ll.245 (3), b = 12.547 (2), c = 15.043 (3) A, Z = 4, Dc = 1.429 g.cm " V = 2122.5A3, final R = 0.041 for 2008 observed reflections.N-carbomethoxy-11-methoxy-12-hydroxy-kopsinaline: Mr = 458.52, mono-clinic, P21, a = 8.424 (2), b = 13.037 (1), c = 9.883 (1) A, β = 90.14 (2) °, Z = 2, Dc = 1.403 g · cm -3, V = 1085.4 A3, final R = 0.039 for 1687 observed reflections.In the structures: The rings A, B and E (I) take envelop conformations. The ring C takes chair conformation and the ring D boat conformation. There are intramolecular hydrogen bonds 0 (5) -HO (5) Both in molecule (I) and molecule (II), which forms the distorted seven-membered ring with atoms C (22), N (1), C (2), and C (18).