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对丁苯橡胶作业１７２对夫妻的自然流产情况进行了观察和染色体检查，并以包装工１５４对夫妻做对照组。自然流产率分别为９．３％和３．４％，Ｐ＜０．０１；染色体异常率分别为５．８％和０．６％，Ｐ＜０．０１；对接触组流产胚胎９例、对照组５例的绒毛进行检查，染色体异常率分别为６７％及未检出，Ｐ＜０．０１。另对橡胶车间空气中主要毒物苯、苯乙烯的浓度做了测定，苯浓度为１２．３～４２．４ｍｇ／ｍ３，苯乙烯为２９．４～７３．２ｍｇ／ｍ３。结果表明，丁苯橡胶生产对自然流产和染色体异常具有明显影响。
172 cases of spontaneous abortion of styrene-butadiene rubber (SBR) operation were observed and examined by chromosome, and 154 couples were used as control group. The spontaneous abortion rates were 9.3% and 3.4% respectively, P <0.01; chromosomal abnormalities were 5.8% and 0.6%, respectively, P <0.01; The control group of 5 cases of villi were examined, chromosomal abnormalities were 67% and were not detected, P <0.01. In addition, the concentrations of benzene and styrene in the air of rubber workshop were measured. The concentration of benzene was 12.3-42.4mg / m3 and that of styrene was 29.4-73.2mg / m3. The results show that styrene butadiene rubber production on spontaneous abortion and chromosomal abnormalities have a significant impact.