论文部分内容阅读
目的观察依贝沙坦对伴或不伴高血压 2型糖尿病 (DM2 )患者血压的影响。方法对服用依贝沙坦的 40例伴高血压与 42例不伴高血压及 3 0例未服任何降压药 DM2 患者进行 2 4小时动态血压监测 (ABPM)。结果服药后 2个月各期血压均降低 ,尤以夜间血压下降明显 ,与服药前有显著差异 (高血压组 P<0 .0 1,正常血压组 P<0 .0 5 ) ,且正常血压组血压仍在正常范围。 BPF组服药后升高明显 ,与服药前比较差异显著 (P<0 .0 1)。服药后 4个月各期血压与服药后 2个月无显著差异 (P>0 .0 5 )。对照组前后各期动态血压无显著变化 (P>0 .0 5 )。结论依贝沙坦能有效降低伴高血压 2型糖尿病患者的血压 ,控制不伴高血压 2型糖尿病患者的血压 ,而且是安全的。并且能恢复患者的血压昼夜节律
Objective To observe the effect of irbesartan on blood pressure in patients with and without type 2 diabetes mellitus (DM2). Methods A total of 40 patients with irbesartan and 40 patients with hypertension and 42 patients without hypertension and 30 patients without any antihypertensive drug DM2 were given 24-hour ambulatory blood pressure monitoring (ABPM). Results After 2 months of treatment, the blood pressure decreased at each stage, especially during nighttime blood pressure decreased significantly (P <0.01, hypertension group, P <0.05), and normotensive Group blood pressure is still in the normal range. BPF group after taking medicine significantly increased, compared with before taking a significant difference (P <0. There was no significant difference in blood pressure between the four months after taking the drug and two months after taking the drug (P> 0.05). There were no significant changes in ambulatory blood pressure before and after the control group (P> 0.05). Conclusion Irbesartan can effectively reduce the blood pressure in patients with type 2 diabetes mellitus and control the blood pressure in patients with type 2 diabetes without hypertension and is safe. And can restore the patient’s circadian rhythm