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本文介紹一个大白鼠心肺制备的簡易装置及实驗方法,并对猫、狗及綿羊三种异种血液灌注結果作了描述。猫及狗血灌注效果較好,成功率高;而綿羊血灌注效果較差,也不恒定。利用肺外氧合法代替正压人工呼吸可减輕实驗过程中发生肺水肿,延长心肺制备存活的时間。对于长时間灌注,以外周阻力使血压保持于60—80毫米汞柱水平,血温在35—36℃,供血压在8—10厘米高度为适宜。对影响实驗成功及存活时間的因素略加討論。
This article describes a simple device and experimental method for cardiopulmonary preparation in rats and describes the results of three different kinds of blood perfusion in cats, dogs and sheep. Cats and dogs blood perfusion better, a high success rate; and sheep blood perfusion is poor, not constant. The use of pulmonary oxygenation instead of positive pressure artificial respiration can reduce pulmonary edema and prolong the time of cardiopulmonary preparation. For prolonged perfusion, peripheral resistance to maintain blood pressure at 60-80 mm Hg levels, blood temperature at 35-36 ℃, blood pressure at a height of 8-10 cm is appropriate. A slight discussion of the factors that affect the success of the experiment and the duration of its survival.