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目的:探讨在复发性外阴阴道念珠菌病(RVVC)巩固治疗阶段中的合理、有效的治疗方案。方法:将2009年10月至2011年3月在我院妇科门诊确诊为RVVC的患者186例,随机分成2组。在强化治疗后转入巩固治疗中,治疗组选择黄体期(下次月经前1周)口服氟康唑150mg,每3天1次,连用2次/月,共用6个月。对照组不择期口服氟康唑150mg,每周1次,共用6个月。结果:治疗组总有效率95%,对照组总有效率83%,疗效有显著性差异(P<0.05)。结论:黄体期用药治疗复发性外阴阴道念珠菌病(RVVC)能有效的提高治愈率,降低复发率。
Objective: To explore a reasonable and effective treatment in the treatment of recurrent vulvovaginal candidiasis (RVVC) consolidation. Methods: From October 2009 to March 2011 in our hospital gynecological clinic diagnosed as RVVC in 186 patients, were randomly divided into two groups. Intensive treatment in consolidation therapy, the treatment group choose luteal phase (next week before menstruation) oral fluconazole 150mg, once every 3 days, once every 2 times / month, sharing 6 months. Control group did not elective oral fluconazole 150mg, once a week, sharing 6 months. Results: The total effective rate was 95% in the treatment group and 83% in the control group, with significant difference (P <0.05). Conclusion: Luteal phase drug treatment of recurrent vulvovaginal candidiasis (RVVC) can effectively improve the cure rate and reduce the recurrence rate.