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目的了解淮南市手足口病的流行趋势及病原型别鉴定分析。方法对2010年4～12月123例临床诊断手足口病例进行三间分布分析,采用逆转录-聚合酶链反应(RT-PCR)鉴定肠道病毒病原体型别。结果来自哨点医院123例患者中,中心城区(57例)与其他县区之和(66例)发病人数比例约为1:1.16;手足口病以5月为发病高峰,高发年龄集中在1～5岁年龄组,男性患者(85)与女性患者(38)比例约为1:0.45;123份咽拭子标本病原鉴定阳性数95例,阳性率77.2%(EV71:CA16约为2:1)。结论淮南市手足口病的流行在地域分布无明显的地域差别,有明显的流行季节及年龄分布,患者以EV71感染为主,同时伴有CA16及其他型别肠道病毒感染。
Objective To understand the epidemic trend and pathogen type identification of hand-foot-mouth disease in Huainan. Methods Three cases of 123 clinical cases of hand, foot and mouth were analyzed from April to December in 2010, and the pathogen of enterovirus was identified by reverse transcription polymerase chain reaction (RT-PCR). Results Among the 123 patients from the sentinel hospital, the ratio of central urban area (57 cases) to the sum of other districts (66 cases) was about 1: 1.16. Hand-foot-mouth disease peaked in May and peaked at 1 In the 5-year-old group, the ratio of male patients (85) to female patients (38) was about 1: 0.45. There were 95 positive cases in 123 throat swab specimens with a positive rate of 77.2% (EV71: CA16 was about 2: 1 ). Conclusion There is no obvious regional difference in the distribution of hand-foot-mouth disease in Huainan city. There are obvious epidemic season and age distribution. The patients are mainly infected with EV71, accompanied by CA16 and other types of enterovirus infection.