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综述了近几年对映体/对映体、对映体/片用药物在药动学中的相互作用.提出药动学相互作用研究中考虑立体选择性因素具有十分重要的临床意义,例如,避免相互作用引起的不良反应、增加治疗效果、理解血药浓度量效关系不一致现象以及提供研究生长点以进一步探求代谢处置机理等.应加强对立体选择性药动学相互作用的研究.
The interaction between enantiomers / enantiomers / enantiomers / tablets in pharmacokinetics has been reviewed in recent years.It is of great clinical significance to consider stereoselective factors in pharmacokinetic interactions , To avoid adverse reactions caused by the interaction, to increase the therapeutic effect, to understand the inconsistency of dose-effect relationship of plasma concentration and to provide a research growing point to further explore the mechanism of metabolic treatment, etc. The study on stereoselective pharmacokinetic interactions should be strengthened.