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目的:比较氟康唑与伊曲康唑对老年患者肺部真菌感染患者的临床疗效与安全性。方法:选取2013年1月—2015年1月间收治的老年肺部真菌感染患者120例为观察对象,将其随机分为对照组和实验组,每组60例;对照组患者均给予伊曲康唑治疗,实验组患者均给予氟康唑治疗,比较两组临床治疗效与安全性。结果:实验组患者治疗后的总有效率为100.00%高于对照组为85.00%(P<0.05);不良反应的发生率明显低于对照组(P<0.05)。结论:采用氟康唑治疗老年肺部真菌感染患者的疗效优于伊曲康唑的疗效。
Objective: To compare the clinical efficacy and safety of fluconazole and itraconazole in elderly patients with pulmonary fungal infection. Methods: A total of 120 elderly patients with pulmonary fungal infection who were admitted to our hospital from January 2013 to January 2015 were enrolled in the study. They were randomly divided into control group and experimental group, 60 cases in each group. Patients in the control group were given Yiqi Conazole treatment, the experimental group were given fluconazole treatment, the clinical efficacy and safety of the two groups were compared. Results: The total effective rate of the experimental group after treatment was 100.00% higher than that of the control group (85.00%, P <0.05). The incidence of adverse reactions was significantly lower than that of the control group (P <0.05). CONCLUSIONS: The efficacy of fluconazole in the treatment of elderly patients with pulmonary fungal infection is superior to that of itraconazole.