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抗高血压药物的主要作用是降低血压,其严重的副作用是引起低血压,尤其是直立性低血压,而交感神经节阻滞药则更易发生。高血压病人服复方降压片后,有较明显的降压作用,临床应用中也见到有低血压的副作用。复方降压片中的主要成分为利血平、双肼哒嗪及双氢克尿塞。而利血平过去曾应用于治疗血压正常的窦性心律过速患者,亦曾有低血压出现。我校药理教研室也曾观察到利血平对正常血压的实验动物有降压作用。鉴于利血平的降压机制可能由于该药有阻止囊泡对介质的再摄取,破坏它的储存介质的机能及减少去甲肾上腺素的合成,故可同样作用于正
The main role of antihypertensive drugs is to lower blood pressure, and its serious side effects are hypotension, especially orthostatic hypotension, while sympathetic ganglia blockers are more likely to occur. Hypertensive patients taking compound antihypertensive tablets, there is more obvious antihypertensive effect, clinical application also saw the hypotensive side effects. Compound antihypertensive tablets in the main components of reserpine, double hydrazine pyridazine and hydrochlorothiazide. While reserpine has been used in the past to treat patients with normotensive sinus rhythm, there have been hypotension. Department of Pharmacology, our school has also observed reserpine normal blood pressure in experimental animals have antihypertensive effect. Given that the antihypertensive mechanism of reserpine may act on positives as the drug may prevent the vesicles from reabsorbing the media, disrupting the functioning of its storage medium, and decreasing noradrenaline synthesis