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目的探讨经尿道前列腺等离子剜除术和切除术治疗巨大前列腺增生的安全性。方法回顾性分析2012年1月至2014年5月在我院接受治疗的巨大前列腺增生患者40例,将所有患者按照治疗方法分为两组,其中观察组15例,采取PKEP予以治疗,对照组15例,采取PKRP进行治疗,比较两组手术方式的安全性。结果两组术中冲洗液吸收量、手术时间、出血量、膀胱冲洗时间等差异明显(P<0.05),有统计学意义。术后随访6个月,两组Qmax、IPSS、PVR等指标和手术前比较,均有明显改善(P<0.05);术后6个月,两组间IPSS等改善不明显,但Qmax和PVR的差异较明显(P<0.05),有统计学意义。结论两种手术方式比较,安全性无明显区别;PKEP组组织标本获得率高于PKRP组,提高了前列腺偶发癌的检出率,且前列腺切除率也比PKRP组高,降低了术后BPH复发率。因此PKEP具有较高的临床应用价值。
Objective To investigate the safety of transurethral resection of prostate and excision for the treatment of giant benign prostatic hyperplasia. Methods Forty patients with giant benign prostatic hyperplasia treated in our hospital from January 2012 to May 2014 were retrospectively analyzed. All the patients were divided into two groups according to the treatment method, of which 15 cases were treated with PKEP, and the control group Fifteen patients were treated with PKRP, and the safety of the two groups was compared. Results The intraoperative fluid uptake, operation time, blood loss, bladder irrigation time and other differences were significant (P <0.05), with statistical significance. After 6 months of follow-up, the Qmax, IPSS, PVR and other indexes in both groups were significantly improved compared with those before operation (P <0.05); 6 months after operation, IPSS and other improvements were not obvious, but Qmax and PVR The difference was more obvious (P <0.05), with statistical significance. Conclusions There is no significant difference in safety between the two surgical approaches. The rate of PKEP group is higher than that of PKRP group, and the detection rate of incidental prostate cancer is increased. The resection rate of prostate cancer is also higher than that of PKRP group, which reduces the postoperative BPH recurrence rate. PKEP therefore has a high clinical value.