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目的探讨小儿腹股沟斜疝发病与腹外斜肌腱膜中Ⅰ、Ⅲ型胶原蛋白表达之间的关系。方法用免疫组化法检测腹股沟斜疝患儿和非疝患儿腹外斜肌腱膜中Ⅰ、Ⅲ型胶原蛋白的表达。结果腹股沟斜疝患儿腹外斜肌腱膜中Ⅰ、Ⅲ型胶原蛋白的表达同非疝患儿差异无统计学意义(P>0.05)。结论小儿腹股沟斜疝不是腹外斜肌腱膜中Ⅰ、Ⅲ型胶原蛋白表达异常引起的。
Objective To investigate the relationship between the incidence of oblique inguinal hernia in children and the expression of type Ⅰ and type Ⅲ collagen in the extra-plantar oblique aponeurosis. Methods Immunohistochemical method was used to detect the expression of type Ⅰ and type Ⅲ collagen in the abdominal aponeurosis of children with inguinal hernia and non-hernia. Results The expression of type I and type III collagen in abdominal oblique aponeurosis of children with inguinal hernia was not significantly different from that of children with non - hernia (P> 0.05). Conclusion Inguinal hernia in children is not caused by abnormal expression of type I and type III collagen in the extra-abdominal oblique aponeurosis.