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因子Ⅷ相关抗原(简称ⅧR:Ag)抗血清已初步应用于临床。目前已证实在某些疾病ⅧR:Ag是高的,如肾脏病、肝脏病、恶性肿瘤、糖尿病伴微血管病变等,而在血管性假血友病者则低,故除可用来鉴别血友病甲和血管性假血友病外,而且还可能是反映高凝状态的一项指标,这对研究这些疾病的发病机理具有重要的意义。近年来,我们曾对95例孕妇进行血浆ⅧR:Ag含量测定。现将测定结果介绍如下。资料来源与测定方法本组均系产科门诊及住院孕妇,其中早期妊娠17例,中期妊娠23例,晚期妊娠36例,妊娠高血压综合
Factor Ⅷ related antigen (Ⅷ R: Ag) antiserum has been initially applied in clinical practice. It has been confirmed in some diseases Ⅷ R: Ag is high, such as kidney disease, liver disease, cancer, diabetes with microvascular disease, etc., and in von Willebrand disease is low, it can be used in addition to identifying hemophilia A and von Willebrand disease, but also may be an indicator of hypercoagulable state, which is of great significance for the study of the pathogenesis of these diseases. In recent years, we have 95 cases of pregnant women plasma Ⅷ R: Ag content determination. Now the determination results are as follows. Data sources and determination of this group are obstetric outpatient and inpatient pregnant women, including 17 cases of early pregnancy, 23 cases of interim, late pregnancy in 36 cases, pregnancy-induced hypertension