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目的探讨尿激酶溶栓治疗急性心肌梗死的临床治疗效果。方法回顾性分析我院收治的139例急性心肌梗死患者,随机分为2组,治疗组70例采用尿激酶溶栓治疗,对照组69例采用硝酸脂类联合应用,比较两组疗效。结果治疗组总有效率为90%,对照组总有效率为78.3%,治疗组总有效率明显高于对照组。治疗组2例在溶栓开始60min时出现死亡而无法进行再通,脑出血死亡1例,5例患者出现心律失常;对照组脑出血死亡4例,急性心力衰竭死亡3例,10例出现心律失常。其余患者均完成治疗,康复出院,没有发生严重并发症。结论溶栓治疗可恢复心肌灌注,缩小心肌梗死面积,改善心脏功能,是治疗急性心肌梗死的最有效措施,值得在临床中推广。
Objective To investigate the clinical effect of urokinase thrombolytic therapy on acute myocardial infarction. Methods A retrospective analysis of 139 cases of acute myocardial infarction admitted to our hospital were randomly divided into two groups. The treatment group was treated with urokinase thrombolysis, and the control group, 69 cases were treated with nitroglycerin. The curative effect was compared between the two groups. Results The total effective rate was 90% in the treatment group and 78.3% in the control group. The total effective rate in the treatment group was significantly higher than that in the control group. Two patients in the treatment group died at 60min after thrombolysis and could not recanalize. One patient died of intracerebral hemorrhage and five patients had arrhythmia. In the control group, 4 patients died of cerebral hemorrhage, 3 patients died of acute heart failure and 10 patients experienced cardiac rhythm Disorders. The remaining patients were treated, discharged from hospital without serious complications. Conclusion Thrombolytic therapy can restore myocardial perfusion, reduce myocardial infarct size, improve cardiac function, is the most effective measure for the treatment of acute myocardial infarction, it is worth in the clinic.