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目的 :观察左氧氟沙星和头孢呋辛治疗鼻窦炎的临床疗效。方法 :随机选择急、慢性鼻窦炎患者 ,用左氧氟沙星和头孢呋辛两组进行 2周口服治疗 ,左氧氟沙星组 76例 ,头孢呋辛组 14例。治疗前后进行临床和实验室检查 ,2周后进行疗效和安全性评估。结果 :左氧氟沙星组有效率为 97.4% ,头孢呋辛组为 92 .8% ;细菌清除率两组分别为 91.6 %和 80 .0 %。两组均有较高安全性。结论 :左氧氟沙星是治疗急、慢性鼻窦炎的有效药物 ,治疗时应注意用药疗程。
Objective: To observe the clinical efficacy of levofloxacin and cefuroxime in the treatment of sinusitis. Methods: Randomly selected patients with acute and chronic sinusitis were treated with levofloxacin and cefuroxime two weeks orally, 76 in levofloxacin group and 14 in cefuroxime group. Clinical and laboratory tests were performed before and after treatment, and efficacy and safety assessments were performed two weeks later. Results: The effective rate of levofloxacin group was 97.4% and that of cefuroxime group was 92.8%. The bacterial clearance rate was 91.6% and 80.0% in the two groups respectively. Both groups have higher safety. Conclusion: Levofloxacin is an effective drug for the treatment of acute and chronic sinusitis. Treatment should pay attention to the medication course.