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进行性半侧颜面萎缩畸形（PFHA）是一种少见的机能紊乱综合征，主要以单侧面部萎缩为特征。目前其病因尚不明确，临床表现多样，有多种方法可运用于面部软、硬组织重建，包括自体脂肪游离移植术、组织皮瓣移植技术、正颌外科、骨移植、人工材料填充等。 PFHA患者的病情进展时间较长，临床治疗方法多样，目前尚无有效的治疗方法。因此，最大程度地改善患者面部的对称性和功能是外科治疗的关键。“,”Progressive facial hemiatrophy(PFHA) is an uncommon dysfunction syndrome,characterized by a slow and progressive atrophy affecting one side of the face .Its etiology is not clear and clinical manifesta-tions are various.There are a variety of methods applied to reconstruct soft and hard tissue,including free autologous fat graft,tissue flap transplantation,bone graft,orthognathic surgery,microvascular reconstruction, artificial materials filling etc.The progression of is often long,and the therapies are varied but there is still no curative treatment.Therefore maximum improvement of facial symmetry and function is the key to surgical treatment.