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对２１３例老年慢性肝病患者的乙型肝炎病毒（ＨＢＶ）和丙型肝炎病毒（ＨＣＶ）血清标志物检测发现：ＨＢＶ感染占７３．２４％、ＨＢＶｆｏＨＣＶ重叠感染占１５．４９％、ＨＣＶ感染占７．０４％、其它占４．２６％；ＨＢＶ阴性者ＨＣＶ检出率高于ＨＢＶ阳性者，肝癌和肝硬化患者较慢性肝炎患者高（Ｐ＜０．０１）；ＨＢＶ和ＨＣＶ重叠感染患者的血清白蛋白下降显著，γ－球蛋白升高明显，肝硬化并腹水和上消化道出血者多（Ｐ＜０．０１或Ｐ＜０．０５）。结果表明，老年慢性肝病患者以ＨＢＶ感染为主，其次是ＨＢＶ和ＨＣＶ重叠感染。重叠感染患者病情重、并发症多、预后差。
The detection of hepatitis B virus (HBV) and hepatitis C virus (HCV) serum markers in 213 elderly patients with chronic liver disease found that HBV infection accounted for 73.24%, HBVfoHCV overlap infection 15.49% and HCV infection 7 .04%, and others accounted for 4.26%. The positive rate of HCV in HBV-negative patients was higher than that in HBV-positive patients, the patients with liver cancer and cirrhosis were significantly higher than those with chronic hepatitis (P <0.01) Albumin decreased significantly, γ-globulin increased significantly, cirrhosis and ascites and upper gastrointestinal bleeding were more (P <0.01 or P <0.05). The results showed that the elderly with chronic hepatitis B virus infection, followed by HBV and HCV overlap infection. Overlapping patients with severe illness, complications and poor prognosis.