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目的分析造血干细胞移植患者进行PICC或CVC置管导致导管感染的原因,并总结有效的预防护理措施。方法患者于造血干细胞移植前行PICC或CVC置管,并给予规范化的观察与护理。当患者体温≥37.5℃时,予以从导管和外周静脉同时抽血做定量血培养,导管和外周静脉血培养都呈阳性,并为同一微生物时,确定导管感染。结果 245例患者中13例发生导管感染,发生率5.3%,12例患者拔出了导管,1例患者根据药敏实验结果,积极治疗后,感染得到控制。结论造血干细胞移植患者在处于粒缺状态时,必需采取积极有效的护理措施。当导管感染发生后,应及时拔出导管并根据药敏实验给予积极治疗。
Objective To analyze the causes of catheter infection caused by PICC or CVC in patients with hematopoietic stem cell transplantation and to summarize the effective preventive measures. Methods Patients undergoing PICC or CVC catheterization before hematopoietic stem cell transplantation were given standardized observation and nursing. When the patient’s body temperature ≥37.5 ℃, blood was drawn from the catheter and peripheral vein to do quantitative blood culture, catheter and peripheral venous blood cultures were positive, and for the same microorganisms, to determine catheter infection. Results Of the 245 patients, 13 had catheterization with a prevalence of 5.3%. Twelve patients underwent catheterization. One patient underwent antibiotic susceptibility testing after active treatment and the infection was controlled. Conclusion In patients with hematopoietic stem cell transplantation in the absence of state, it is necessary to take active and effective care measures. When the catheter infection occurs, catheter should be pulled out in time and given positive treatment according to drug sensitivity test.