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笔者选择 1992～ 1996年间 ,安徽某乡“职业”供血员和 2所省级医院住院病人中 ,抗 -HCV( +)和 /或 HCV RNA( +)者为调查对象。追访了他们 HCV感染及其后的有关重要临床诊治和流行病学信息 ,同时调查了感染者的现况及相关实验室指标检测 ,描述了供血员人群丙型肝炎病毒感染后慢性转化率变化趋势。结果 HCV感染 6个月后慢性转化率为 55.93% ,1～ 4年慢性转化率依次为 50 %、4 8.54%、4 6.4 7%和 4 6.4 3%。表明其感染后慢性转化率一直持续高水平 ,下降缓慢 ,尤其 2年后基本稳定在 4 6%～ 4 8% ,远高于乙型肝炎 5%～ 10 %的慢性转化率。
The author chooses the anti-HCV (+) and / or HCV RNA (+) among the “professional” blood donors and the inpatients of two provincial hospitals from 1992 to 1996 in our country. They were interviewed for their HCV infection and subsequent important clinical diagnosis and epidemiological information. Meanwhile, the status of infected persons and related laboratory tests were investigated. The changes of chronic conversion rate after infection with hepatitis C virus in blood donors were described trend. Results After 6 months of HCV infection, the chronic conversion rate was 55.93%. The chronic conversion rates from 1 to 4 years were 50%, 4 8.54%, 6.47% and 6.43%, respectively. The results showed that chronic infection rate continued to be high and declined slowly after infection, especially after 4-6 years, basically stable at 4-6% to 48%, much higher than the chronic conversion rate of 5% -10% of hepatitis B virus.