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病毒性心肌炎(以下简称V.M.C)使用肾上腺糖皮质激素(以下简称激素)治疗的利弊问题,历来颇有争论,深为临床医师关注。本文就病毒性心肌炎治疗中使用激素的有关资料及临床体会加以讨论。一、激素治疗V.M.C的理论基础: V.M.C的病理生理改变:一般认为早期主要由病毒及毒素经血液循环直接侵犯心肌细胞产生病理变化,可致心肌细胞发生代谢紊乱及供血障碍。在病程后期,病毒已不存在时,病变主要由病毒或心肌抗原所诱发的体液及细胞免疫反应所引起。其性质多以心肌间质组织和附近血管周围单核细胞、淋巴细胞及中性粒细胞浸润为主,少数可致心肌肿
Viral myocarditis (hereinafter referred to as V.M.C) The use of adrenal glucocorticoid (hereinafter referred to as hormone) the advantages and disadvantages of treatment, has always been controversial and deeply concerned about clinicians. This article discusses the use of hormones in the treatment of viral myocarditis and clinical experience to be discussed. First, the theoretical basis of hormone therapy V.M.C: V.M.C pathophysiological changes: It is generally believed that the early mainly by the virus and toxins through the blood circulation directly invade cardiomyocytes to produce pathological changes, can cause myocardial cell metabolic disorders and blood supply disorders. Late in the course of the disease, the virus is no longer present, the disease is mainly caused by viral or cardiac antigen induced humoral and cellular immune responses. Its nature and more myocardial stromal tissue and nearby perivascular monocytes, lymphocytes and neutrophil infiltration, a few can cause myocardial swelling