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目的 探索判定大肠粘膜异型增生的计量学指标。方法 采用MPLAS-500型病理图文分析系统,检测大肠粘膜异型增生20例,设大肠CAR、NOR为对照组,测量参数为CyA、PA、NA、Pn、NF、N/P。结果 MDYS与NOR的六项参数均有明显差异(P<0.01);MDYS与CAR的五项参数有显著差异(P<0.01、P<0.05),而两者的NF未见明显差异(P>0.05);CAR与NOR有五项参数见有显著差异(P<0.01、P<0.05),而两者的CyA无明显差异(P>0.05);三组的NF和N/P 95％可信区间无重叠。结论 细胞计量学指标能反映大肠异型增生的形态特征,三组的NF和N/P 95％可信区间无重叠,表明大肠异型增生的诊断可考虑客观数据化。
Objective To explore the metrological indicators for judging dysplasia of the large intestine mucosa. METHODS: MPLAS-500 pathological graphic analysis system was used to detect 20 cases of dysplasia of colorectal mucosa. CAR and NOR were used as control group. The parameters were CyA, PA, NA, Pn, NF and N/P. Results The six parameters of MDYS and NOR were significantly different (P<0.01); the five parameters of MDYS and CAR were significantly different (P<0.01, P<0.05), and there was no significant difference in NF between the two parameters (P>0.05). 0.05); CAR and NOR have five parameters have significant differences (P <0.01, P <0.05), and no significant difference between the two CyA (P> 0.05); three groups of NF and N / P 95% trusted There is no overlap in the intervals. Conclusion The cytometric indicators can reflect the morphological characteristics of large intestine dysplasia. The NF and N/P 95% confidence intervals of the three groups have no overlap, indicating that the diagnosis of large intestine dysplasia can be objectively dataized.