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检测167例各类肝病患者的几种血浆凝血因子。22例息肝FⅦ:CA为90.1±24.6%,与正常组(107.5±14.5%)比较,有显著性差异(P<0.05);26例肝硬化及20例重肝FⅦ:CA分别为38.8±10.4%及29.8±23.9%,与正常组比较,P<0.001。检测37例急肝Fg。Ag为4.06±1.04g/L,显著高于正常组(2.88±0.67g/L),P<0.05;38例肝硬化和30例重肝Fg。Ag分别为1.86±0.64g/L及0.163±0.095g/L,与正常组比较,P<0.001。各类FⅧ:CA、VWF:Ag/Ⅶ:CA、VWF:Ag均高于正常组(P<0.01)。因此,上述测定对观察疗效及判断病情有参考意义。VWF:Ag/Ⅶ:Ag对诊断肝病并发DIC有重要意义。
Several kinds of plasma coagulation factors were detected in 167 cases of various liver diseases. There were significant differences between the two groups (P <0.05). The percentages of FⅦ: CA in 22 cases were 90.1 ± 24.6%, which were significantly different from those in normal group (107.5 ± 14.5% 10.4% and 29.8 ± 23.9% respectively, P <0.001 compared with the normal group. 37 cases of acute liver Fg were detected. Ag was 4.06 ± 1.04g / L, significantly higher than the normal group (2.88 ± 0.67g / L), P <0.05; 38 cases of liver cirrhosis and 30 cases of severe liver fibrosis. Ag were 1.86 ± 0.64g / L and 0.163 ± 0.095g / L respectively, P <0.001 compared with the normal group. All kinds of F Ⅷ: CA, VWF: Ag / Ⅶ: CA, VWF: Ag were higher than those in normal group (P <0.01). Therefore, the above determination of the observed efficacy and judgment of the disease have reference value. VWF: Ag / Ⅶ: Ag is important in the diagnosis of liver disease complicated with DIC.