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目的探讨莫沙必利联合胆石通治疗老年功能性便秘患者的临床效果。方法选取2012年8月至2015年1月河南省唐河县公疗医院收治的80例老年功能性便秘患者作为研究对象,按照随机数字表法将其分为观察组和对照组,各40例。对照组患者口服胆石通,观察组患者在对照组基础上采用莫沙必利,比较两组治疗前后结肠传输功能、临床疗效及并发症发生情况。结果治疗后48 h、72 h,观察组患者的结肠运输速度均明显快于对照组,差异均有统计学意义(均P<0.05);观察组患者治疗的有效率明显高于对照组,差异有统计学意义(P<0.05)。结论莫沙必利联合胆石通胶囊治疗老年功能性便秘患者临床疗效明显,能明显改善患者结肠传输功能,安全性高。
Objective To investigate the clinical efficacy of mosapride and gallstone in the treatment of elderly patients with functional constipation. Methods Eighty elder patients with functional constipation who were admitted to Tanghe County Public Hospital of Henan Province from August 2012 to January 2015 were selected as study subjects and divided into observation group and control group according to random number table method, . Patients in the control group were treated with gatily stone, and patients in the observation group were treated with mosapride on the basis of the control group. The function of the colon and the clinical efficacy and complications of the two groups were compared before and after treatment. Results At 48 h and 72 h after treatment, the colonic transit speed in the observation group was significantly faster than that in the control group (all P <0.05). The effective rate of treatment in the observation group was significantly higher than that in the control group There was statistical significance (P <0.05). Conclusion Mosapride combined with gallstone capsule in the treatment of elderly patients with functional constipation obvious clinical efficacy, can significantly improve the patient’s colon transport function, high safety.