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目的 研究脑梗塞患者颈动脉粥样硬化斑块与血清氧化低密度脂蛋白 (OX- L DL)、脂蛋白 a(L Pa)的关系。方法 采用酶联吸附试验测定 116例脑梗塞患者血清 OX- L DL、L Pa,再根据颈动脉超声多普乐检查结果 ,将患者分为斑块组、无斑块组 ,对比分析。结果 斑块组 OX- L DL高于无斑块组 ,而 L Pa显著低于无斑块组。结论 OX- L DL增高是促进斑块形成的重要因素 ,颈动脉粥样硬化斑块形成以后 L Pa反而下降。
Objective To investigate the relationship between carotid atherosclerotic plaques and serum levels of oxidized low density lipoprotein (OX-L DL) and lipoprotein (L Pa) in patients with cerebral infarction. Methods Serum levels of OXL-L and L-Pa were measured in 116 patients with cerebral infarction by enzyme-linked immunosorbent assay. According to the carotid ultrasonography, the patients were divided into plaque group and no plaque group. Results The level of OX-L DL in plaque group was higher than that in non-plaque group and L Pa was significantly lower than that in non-plaque group. Conclusion The increase of OX-L DL is an important factor to promote plaque formation. L Pa decreases after carotid atherosclerotic plaque formation.