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为研究颇利肝胶囊(PLGC)对小鼠免疫功能的影响,分别观察了PLGC对小鼠巨噬细胞吞噬功能和血清溶血素的影响,以及对巨噬细胞分泌白介素-1、白介素-2的影响。结果:实验组吞噬指数和吞噬系数均较对照组明显升高(P<0.01);50mg/kg和100mg/kg实验组的半数溶血值较对照组明显升高(P<0.01);实验组PLGC可恢复由环磷酰胺所抑制的小鼠巨噬细胞分泌白介素-1的能力;实验组较对照组显著提高小鼠脾细胞生成白介素-2的能力(P<0.05~0.01)。结果显示,PLGC具有增强小鼠细胞和体液免疫功能的作用
In order to study the effect of PLGC on immune function in mice, we observed the effect of PLGC on macrophage phagocytosis and serum hemolysin, and the effect of PLGC on the secretion of interleukin-1 and interleukin-2 by macrophages influences. Results: The phagocytic index and phagocytic index of the experimental group were significantly higher than those of the control group (P <0.01). The half hemolytic values of the 50 mg / kg and 100 mg / kg groups were significantly higher than those of the control group (P <0.01) ; Experimental group PLGC can recover cyclophosphamide inhibited mouse macrophage secretion of interleukin-1; experimental group than the control group significantly increased the ability of mouse spleen cells to produce interleukin -2 (P <0.05 ~ 0 .01). The results showed that, PLGC has a role in enhancing mouse cellular and humoral immune function