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自从发现糖酯及硫苷类化合物具有抗菌、抗肿瘤等广泛的生理活性以来,有关这两类化合物的合成及其性质研究已成为人们极为关注的课题。但具有某些生理活性的三唑羧酸类和巯基嘧啶类化合物与糖基形成糖酯和硫苷的有关合成尚未见文献报道。为了寻找高效低毒的化合物,本文通过相转移催化法,在温和的反应条件下,立体专一性地合成了吡喃型
Since the discovery of sugar esters and glucosinolates with a wide range of physiological activities such as anti-bacterial and anti-tumor, the research on the synthesis and properties of these two compounds has become a subject of great concern. However, some biologically active triazole carboxylic acids and mercapto pyrimidines with glycosyl sugar ester and glucosinolate synthesis has not been reported in the literature. In order to search for compounds with high potency and low toxicity, we synthesized the pyran type stereoselectively under mild reaction conditions by phase transfer catalysis