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患有严重肺脏血流梗阻的新生儿有赖于动脉导管持久开放而得以保持体循环中足够的含氧量。本文作者对19例这类患儿用静脉输注前列腺素E(PGE_1)的方法以求获得动脉导管的持久开放。患儿分别在生后24小时至9天内经头皮静脉输注PGE_1,在5小时到13天内间歇给药,剂量为0.025～0.3μg/kg/分。治疗后,19例患儿的动脉血氧分压均显著升高
Neonates with severe pulmonary blood flow obstruction rely on the persistent open ductus arteriosus to maintain adequate systemic oxygen levels. The authors of this series of 19 children with this type of intravenous infusion of prostaglandin E (PGE_1) method in order to obtain the long-term open ductus arteriosus. Children were transplanted via the scalp vein with PGE 1 within 24 hours to 9 days after birth, intermittently within 5 hours to 13 days at a dose of 0.025-0.3 μg / kg / min. After treatment, 19 cases of children with arterial partial pressure of oxygen were significantly increased