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自70年代早期世界卫生组织(WHO)的人类生殖研究、发展、培训特别规划成立之后,就开始致力于研究和建立新的生殖调节方法。今天,据专家们估计,所有发展中国家大约有6亿育龄夫妇,其中大约80%的人因各种原因而未采取适当的生殖控制方法。因此,研制一种新的、有效、安全、价廉的节育方法对世界各国,特别是发展中国家来说是尤为迫切的愿望。生殖调节疫苗是一个令人注目的领域,1985年4月,WHO的专家组回顾讨论了疫苗制备中生殖特异性抗原的研究进展,确定了作为生殖控制疫苗抗原所须达到的标准和有关抗原研究和测定中新技术的应用。专家们认为制备一种可以接受的生殖调节疫苗的靶抗原,下列因素是重要的,即抗原应是
Since the establishment of the World Health Organization (WHO) Special Program for Research, Development and Training of Human Reproduction in the early 1970s, it has been devoted to studying and establishing new methods of reproductive regulation. Today, experts estimate that there are about 600 million couples of fertile young age in all developing countries, and about 80% of them are not adopting appropriate methods of reproductive control for a variety of reasons. Therefore, developing a new, effective, safe and inexpensive birth control method is a particularly urgent aspiration for all countries in the world, especially for developing countries. Reproductive regulation vaccine is an attractive area. In April 1985, the WHO expert group reviewed the research progress on reproductive-specific antigens in vaccine preparation, determined the criteria to be met as a vaccine for reproductive-controlled vaccines and related antigen studies And determination of the application of new technologies. Experts believe that the preparation of an acceptable target antigen for reproductive regulation vaccine, the following factors are important, that the antigen should be