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骨髓异常增生症(MDS)中 RAEB—T 型(难治性贫血伴原始细胞增多转化型)易向急性粒细胞白血病演变,治疗十分困难。我们用阿克拉霉素(Acla-cinomycin,日本)治疗 RAEB—T4例,取得较好疗效,现报道如下。例1:刘××,男,35岁,住院号405215。1989年6月低热、贫血、骨髓穿刺原始细胞Ⅰ+Ⅱ型9%。诊断为 RAEB(难治性贫血伴原始细胞增多),使用小剂量阿糖胞苷20mg×15天共3个疗程,病情稳定为12个月。1990年6月因头昏、乏力、牙龈出血再次入院,骨穿显示原始细胞Ⅰ+Ⅱ型为
In myelodysplastic syndromes (MDS), RAEB-T (refractory anemia with proliferative primary) is predisposed to acute myeloid leukemia and its treatment is very difficult. We use aclacinomycin (Acla-cinomycin, Japan) treatment of RAEB-T4 cases, and achieved good efficacy, are reported below. Example 1: Liu XX, male, 35 years old, hospital number 405215. June 1989 Low fever, anemia, bone marrow aspirate primitive cells type I + Ⅱ 9%. The diagnosis of RAEB (refractory anemia with an increase of primitive cells), the use of small doses of cytarabine 20mg × 15 days a total of three courses, stable condition for 12 months. 1990 June due to dizziness, fatigue, gingival bleeding again hospitalized, bone wear shows primary cells Ⅰ + Ⅱ type is