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目的探讨引起足月新生儿高胆红素血症的病因及相关高危因素。方法回顾性分析2008年8月-2011年5月我院收治的210例足月新生儿的临床资料,对可能引起高胆红素血症的因素进行分类并比较总结。结果由于围产期相关因素(胎龄、高龄初产、剖宫产、母乳缺乏、宫内窘迫、羊水污染、妊娠期高血压、产前使用催产素、镇静剂以及胎膜早破等)引起的高胆红素血症患儿占总数的33.3%(70/210),是引起足月新生儿高胆红素血症的主要原因;其次为新生儿感染,占总数的12.4%(26/210)。结论加强围生期保健及护理,严格掌握剖宫产指征以及提倡母乳喂养,是有效预防高胆红素血症的主要措施。
Objective To investigate the etiology and related risk factors of neonatal hyperbilirubinemia in term neonates. Methods The clinical data of 210 full-term newborns admitted to our hospital from August 2008 to May 2011 were retrospectively analyzed. The possible causes of hyperbilirubinemia were classified and compared. Results As a result of perinatal related factors (gestational age, advanced birth, cesarean section, lack of milk, intrauterine distress, amniotic fluid contamination, gestational hypertension, prenatal oxytocin, sedatives and premature rupture of membranes, etc.) 33.3% (70/210) of the patients with hyperbilirubinemia were the main cause of full-term neonatal hyperbilirubinemia, followed by neonatal infection, accounting for 12.4% of the total (26/210 ). Conclusions Strengthening perinatal care and nursing, strictly controlling cesarean section indications and promoting breastfeeding are the main measures to effectively prevent hyperbilirubinemia.