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目的 研究青少年强直性脊柱炎 (Ankylosingspondylitis,AS)早期年龄、身高、体重与腰椎L1 -4骨矿含量 (L1 -4BMC)、腰椎L1 -4骨密度 (L1 -4BMD)的相关性。方法 选择男性青少年AS早期病例 31例。应用DPX -IQ双能X线骨密度仪 (DEXA)检测L1 -4BMC和L1 -4BMD ,分析年龄、身高、体重与L1 -4BMC、L1 -4BMD的关系。结果年龄、身高、体重、L1 -4BMC、L1 -4BMD的测定值分别为 (1 7 5 6± 2 0 1 )岁、 (1 6 8 5 2± 8 5 9)cm、 (5 6 1 3±1 2 72 )kg、 (5 2 1 6± 1 2 1 7)g、 (0 971 1± 0 1 392 ) g/cm2 。L1 -4BMC与身高、体重和年龄呈正相关 (R =0 786 ,Radj2 =0 5 75 ,P <0 0 0 0 1 ) ,其中身高和体重是主要相关因素 (R =0 74 7,Radj2 =0 5 2 6 ,P <0 0 0 0 1 )。年龄、身高和体重因素中仅体重因素进入L1 -4BMD回归方程 (R =0 6 5 7,Radj2 =0 4 1 2 ,P <0 0 0 0 1 )。结论 身高和体重与L1 -4BMC相关 ,体重与L1 -4BMD相关。身高和体重为研究青少年AS早期骨量变化特点及客观评估AS相关性骨质疏松危险性的重要因素
Objective To investigate the correlation between early age, height and weight of ankylosponsive ankylosing spondylitis (AS) and lumbar L1 -4 BMC and L1 -4 BMD of lumbar spine. Methods Thirty - one male cases of early childhood AS were selected. The relationship between L1-4BMC and L1-4BMD was analyzed by DPX-IQ dual-energy X-ray absorptiometry (DEXA). Results The results of age, height and weight, L1 -4 BMC and L1 -4 B BMD were (1765 ± 2091), (1658 ± 859) cm, (5631 ± 1 2 72) kg, (5 2 1 6 ± 1 2 1 7) g, (0 971 1 ± 0 1 392) g / cm2. There was a positive correlation between L1 -4 BMC and height, weight and age (R = 0 786, Radj2 = 0 5 75, P 0 01 0), with height and weight being the major relevant factors (R = 0 747, Radj2 = 0 5 2 6, P <0 0 0 0 1). Body weight, age, height, and weight factors only entered the L1 -4 BMD regression equation (R = 0 6 5 7, Radj 2 = 0 4 1 2, P <0 0 0 0 1). Conclusions Height and weight are related to L1 -4 BMC and body weight is related to L1 -4 BMD. Height and Weight To study the characteristics of early bone mass changes in adolescent AS and to evaluate objectively the risk factors associated with AS-related osteoporosis