Transarterial embolization chemotherapy at early stage after hepatectomy of 45 patients with large h

• 作 者: Li Chao-long ZHU Wei-bing FANG Xue-jun ZHOU jie ZOU Yan-tai LIN Jian-hua LIN Zhi-qi YU Xiao-yuan U Xiang-zhi
• 机 构: Department of Hepatobiliary and Vascular Surgery, Nanfang Hospital, First Military Medical Universit
• 出 处: 中国人民解放军军医大学学报
• 发表日期: 2001年1期
• 关键词: hepatocellular carcinoma hepatectomy postoperative recurrence prevention transar

To investigate the effect of transarterial embolization (TAE) at early stage postoperatively to prevent tumor recurence after hepatectomy in patients with large hepatocellular carcinoma (HCC). Methods: Forty-five volunteer patients with large HCC received TAE 2 to 4 weeks after the hepatectomy. Another 48 patients with large HCC without postoperative TAE treatment served as control. Results: No severe complications associated with TAE or hepatectomy occurred, and follow-up visit of all patients revealed that 1-year recurrence rate for patients with PAE was markedly lower than those without (43.24 %vs 70.73%, P<0.05). Conclusion: The treatment with TAE at early stage after hepatectomy is safe and feasible for the patients with liver function Child-Pugh score not higher than 8, and it may help reduce the postoperative recurrence of hepatocellular carcinoma.