Preparation and preliminary biological evaluation of ^99mTc-ANMdU

来源 :核技术：英文版 | 被引量 : 0次 | 上传用户：cdwkevin

【摘要】

：

Technetium-99m-labeled-5-{2-sulfanylethyl-[2-(2-sulfanylethylamino)acetyl]amino}-methyl-2′-deoxy- uridine (99mTc-ANMdU) was reported. The precursor ANMdU was s

【作者】

：

LU Chunxiong JIANG Quanfu YU H

【机构】

：

SchoolofChemical＆MaterialEngineering,KeyLaboratoryofNuclearMedicine,DepartmentofFoodScience＆Technolo

【出处】

：

核技术：英文版

【发表日期】

：

2010年2期

【关键词】

：

生物制备放射化学纯度评价磷酸盐缓冲液 1HNMR 氯化亚锡分配系数中间体 Synthesis ^99mTc-ANMdU Biodistributi

【基金项目】

：

Supported by National Natural Science Foundation of China （20573048 and 20676051）, Natural Science Foundation of Jiangsu Province （BK200811 l, BK2008112） and Department of Health of Jiangsu Province （

下载到本地 , 更方便阅读

下载此文赞助VIP

声明 : 本文档内容版权归属内容提供方 , 如果您对本文有版权争议 , 可与客服联系进行内容授权或下架

论文部分内容阅读

Technetium-99m-labeled-5-{2-sulfanylethyl-[2-(2-sulfanylethylamino)acetyl]amino}-methyl-2′-deoxy- uridine (99mTc-ANMdU) was reported. The precursor ANMdU was synthesized by six-step reactions and all intermediates were verified with MS and 1HNMR. Using Sn

其他文献

俄媒称歼-20可1：1替换苏-27／30有望装备500架

俄罗斯《军事观察》网近日发表文章称，从2010年底起，中国新一代隐形战斗机的照片开始出现在诸多军事网站上，该机暂时被称为歼-20。不过，因为当时中国官方并未发布任何有关这款战

期刊

苏-27装备军事网站隐形战斗机俄罗斯大偏差中国战机

新型太阳能光伏产品落户新疆哈密

日前，新型太阳能光伏产品——高聚光太阳能项目正式落户新疆哈密市石城子光伏园区，一期工程为20兆瓦。据介绍，这项高聚光太阳能技术有追热功能，即阳光接收仪器可跟随太阳从东到西

期刊

太阳能光伏新疆哈密产品光电转换效率太阳能技术一期工程光接收发电量

A new package：MySAS for small angle scattering data analysis

<正>In this paper,A MySAS package,which is verified on Windows XP,can easily convert two-dimensional data in small angle neutron and X-ray scattering analysis,o

期刊

数据分析小角散射WINDOWS二维数据重复输入输入文件X射线散射数据还原Data analysis Small angle scatterin

Ionizing radiation effect on 10-bit bipolar A/D converter

<正>In this article,radiation effects and annealing characteristics of a bipolar analog-to-digital converter(ADC) are investigated in different biases and dose

期刊

数字转换器辐射效应双极性电离辐射低剂量率ADC退火特性参数变化Bipolar Analog to Digital converters ^60

Design and simulation of time-of-flight neutron reflectometer

<正>In this paper,a time of flight neutron reflectometer model is proposed.According to the original objective inputting physical parameters and expectations,co

期刊

反射模型中子通量飞行时间设计仿真计算机模拟最佳分辨率物理参数Time of flight Neutron reflectometer Des

天龙座方向39亿光年处发现黑洞神秘信号

据国外媒体报道，黑洞作为宇宙中奇特的天体，我们通过认为它们不会发生与超新星爆发类似的物质抛射事件，更多时候认为黑洞可以吞噬一切，物质落入事件视界并形成可视的吸积盘，但有时

期刊

黑洞天龙座信号光年物质抛射事件视界超新星爆发伽马射线暴

GATE simulation based feasibility studies of in-beam PET monitoring in ^12C beam cancer therapy

In comparison with conventional radiotherapy techniques,12C beam therapy has its significant advantage in cancer treatment because the radiation dose are mostly

期刊

放射治疗癌症治疗模拟聚酯正电子发射Bragg峰监测辐射剂量Monte Carlo simulation Heavy-ion therapy

Regulation of the radiosensitivity of tumor cells through HIF-1α dependent intracellular redox statu

Tumor cells often develop resistance to radiotherapy by fractionated radiation possibly due to the heterogeneity and hypoxia in tumor tissue.However,the mechani

期刊

放射敏感性肿瘤细胞细胞内氧化还原照射缺氧诱导因子GSH含量组织缺氧RadiationHypoxia inducible factor-1αR

Tumor targeting of ^125I-labeled anti-EGFR monoclonal antibody LA22 in HT-29 human colon cancer

Epidermal growth factor receptor (EGFR) plays a critical role in proliferation, apoptosis, angiogenesis, invasiveness and distant metastasis of tumors. In this

期刊

表皮生长因子受体125I标记肿瘤侵袭单克隆抗体结肠癌流式细胞仪免疫荧光染色结合特异性Epidermal growth factor recept

Neutron response functions and detection efficiency of a spherical proton recoil proportional counte

<正>The neutron response function and detection efficiency of a spherical proton recoil proportional counter (SP) play key roles in precise measurement of neutr

期刊

正比计数器响应函数探测效率反冲质子中子谱球形GEANT4检测效率Spherical proton recoil proportional cou

Preparation and preliminary biological evaluation of ^99mTc-ANMdU

其他学术论文