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探讨创伤患者急性期血糖(Glu)含量变化与动脉收缩压(SBP)、血氧饱和度(SaO2)及预后的关系。测定31例创伤患者术前的Glu含量,结合SBP、SaO2进行对比研究。结果:创伤组术前Glu(8.14±2.47mmol/L)与正常组(4.72±1.38mmol/L)比较有极显著性差异(t=6.37,P<0.001);SBP<8.0kPa(1kPa=7.5mmHg)与>8.0kPa组比较,Glu(10.32±2.37mmol/L比6.74±1.32mmol/L)和SaO2(0.74±0.37比0.91±0.11)均有极显著性差异(P均<0.001),并且SBP越低,Glu越高,SaO2呈直线下降;术前Glu与患者的预后也显著相关,死亡组术前Glu(12.53±1.73mmol/L)明显高于存活组(7.35±1.56mmol/L),而SBP(4.29±4.13kPa)、SaO2(0.29±0.06)则明显低于存活组(分别为10.86±1.78kPa和0.88±0.08,P<0.001)。作者结合文献复习就创伤患者高血糖的发生机制、对预后的影响及处理等问题进行了探讨
To investigate the relationship between the changes of blood glucose (Glu) and arterial systolic pressure (SBP), blood oxygen saturation (SaO2) and prognosis in acute trauma patients. Preoperative determination of the content of Glu in 31 cases of trauma patients, combined with SBP, SaO2 comparative study. Results: The preoperative Glu (8.14 ± 2.47mmol / L) in trauma group was significantly different from that in normal group (4.72 ± 1.38mmol / L) (t = 6.37, P <0.001 ); Glu (10.32 ± 2.37mmol / L vs 6.74 ± 1.32mmol / L) and SaO2 (0.74mmol) compared with SBP <8.0kPa ± 0.37 vs 0.91 ± 0.11) (P <0.001). The lower the SBP, the higher Glu, the lower the SaO2. The prognosis of patients with preoperative Glu (12.53 ± 1.73mmol / L) in the death group was significantly higher than that in the survival group (7.35 ± 1.56mmol / L), while SBP (4.29 ± 4.13kPa), SaO2 0.29 ± 0.06) was significantly lower than the survival group (10.86 ±, respectively) 1.78 kPa and 0.88 ± 0.08, P <0.001). The author reviews the literature on the pathogenesis of hyperglycemia in trauma patients, the impact on prognosis and treatment and other issues were discussed