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化学药物引起急性溶血性贫血文献累见报告,因铜中毒引起急性溶血性贫血者 Dacie(1967)曾发现一例,鉴于波尔多液在农村和园林应用较广,为引起重视,现将本院收治的一例报告如下。患者女性,20岁,住院号55611,于83年8月18日上午口服波尔多液约250ml,后出现恶心、呕吐,在当地卫生院急救,随后畏冷、发烧,19日下午发现尿呈酱油水样,腰酸,皮肤及巩膜发黄,20日转入本院。平素健康,无贫血及黄疸史,病前未服其他药物。体检:体温36.5℃,贫血貌,皮肤及巩膜黄染,淋巴结不肿大,肝大1 cm,脾未触及。实验室检查:Hb 3g,RBC 100万,WBC 14100,网织红细胞4～16%。尿酱油色,红细胞(一),血红蛋白定性阳性,尿胆元(十),胆红质(一)。黄疸指数58单位,间接胆红质阳性,GPT 正常,血尿素氮22.6mg%。骨髓细胞学检查,红细胞系列增生明显活跃,晚幼红及成熟红细胞可见嗜碱点彩。按急性溶贫治疗,每日给氢化可的松200mg 静滴,
Acute hemolytic anemia caused by chemical literature Reportedly reported, due to copper poisoning caused by acute hemolytic anemia Dacie (1967) had found a case, given Bordeaux mixture widely used in rural areas and gardens, for attention, now admitted to our hospital A case report is as follows. Female patient, 20 years old, hospital number 55611, on August 18, 83 orally Bordeaux mixture orally about 250ml, nausea, vomiting, first aid at a local hospital, followed by cold and fever, 19 found urine was soy sauce water Like, backache, skin and sclera yellow, transferred to the hospital on the 20th. Usually healthy, no history of anemia and jaundice, before the disease is not taking other drugs. Physical examination: body temperature 36.5 ℃, anemia appearance, skin and sclera yellow dye, lymph node does not enlarge, liver 1 cm, spleen not touched. Laboratory tests: Hb 3g, RBC 1 million, WBC 14100, reticulocyte 4 ~ 16%. Urine soy sauce color, red blood cells (a), qualitative positive hemoglobin, urinary gallbladder (ten), bilirubin (a). Jaundice index 58 units, indirect bilirubin-positive, GPT is normal, blood urea nitrogen 22.6mg%. Bone marrow cytology, erythrocyte series hyperplasia was significantly active, late red and mature red blood cells can be seen basophilic stippling. Press acute acute lean treatment, hydrocortisone daily 200mg intravenous infusion,