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为研究角化细胞生长因子（KGF）局部应用对鼓膜（TM）穿孔的作用，以38只成年SPraguc－Dawley鼠为对象，麻醉后经耳显微手术切除后1／2TM，遗留纤维鼓环和覆盖相骨的TM。为减少动物之间的差异，每一动物均以自身为对照，随机将左或右耳分为治疗组或对照组。治疗耳分为50μl甘油
To investigate the effect of topical application of keratinocyte growth factor (KGF) on the perforation of the tympanic membrane (TM), 38 adult SPraguc-Dawley rats were enucleated and 1 / 2TM, Cover the phase bone TM. To reduce the differences between animals, each animal used itself as a control and randomly divided the left or right ear into treatment or control groups. The treatment ear is divided into 50 μl glycerol