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过敏性紫癜是一种毛细血管变态反应性疾病,系致敏物质进入人体引起免疫复合物的沉积,诱发血小板凝集,从而释放化学介质,其结果又促使了免疫复合物的沉积。主要侵害皮肤,肠道及肾小球基底膜外<0.1mm的毛细血管及小静脉。该病既往多用皮质激素治疗。但近年有人指出皮质激素有促进血小板的凝集作用,且治疗后多复发,副作用多之弊。近年,随着药理学及临床医学的进展,发现许多老药新用治疗过敏性紫癜取得了可喜效果,本文就此加以概述。 1.潘生丁治疗过敏紫癜。孙氏设观察组61例,对照组58例,两组除常规治疗外,观察组加用潘生丁2.5-5mg/kg,日2-3
Henoch-Schonlein purpura is a capillary allergic disease, the Department of allergens into the body caused by the immune complex deposition, induced platelet aggregation, which releases the chemical mediators, the result in turn prompted the deposition of immune complexes. The main invasion of the skin, gut and glomerular basement membrane <0.1mm capillaries and venules. The disease in the past with corticosteroids. However, in recent years it was pointed out that corticosteroids can promote platelet aggregation, and more recurrence after treatment, the side effects of many disadvantages. In recent years, with the progress of pharmacology and clinical medicine, it has been found that many new old medicines have achieved encouraging results in the new treatment of Henoch-Schonlein Purpura. This article will give an overview of this. 1. Dipyridamole treatment of allergic purpura. Sun set observation group of 61 cases, control group of 58 cases, two groups in addition to conventional treatment, the observation group with dipyridamole 2.5-5mg / kg, day 2-3