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目的探讨宫腔镜联合屈螺酮炔雌醇对子宫内膜息肉的临床治疗效果。方法 91例子宫内膜息肉患者,随机分成观察组(46例)和对照组(45例)。对照组患者于术后接受其他方式治疗,观察组患者于术后当日开始服用屈螺酮炔雌醇。治疗6个月后,观察两组患者复诊检查结果 ,了解子宫内膜息肉复发情况。结果治疗后,观察组2例复发者,复发率为4.3%,对照组8例复发者,复发率为17.8%,观察组患者复发率明显低于对照组(P<0.05)。观察组45例患者月经恢复正常,占97.8%(45/46);对照组35例患者月经恢复正常,占77.8%(35/45),观察组月经恢复率明显高于对照组(P<0.05)。观察组出现4例头痛恶心,占8.7%(4/46),3例情绪波动大,占6.5%(3/46),2例月经期出血,占4.3%(2/46),不良反应率为19.6%(9/46);对照组出现0例头痛恶心,4例情绪波动大,占8.9%(4/45),4例月经期出血,占8.9%(4/45),不良反应率为17.8%(8/45);两组患者不良反应发生率比较差异无统计学意义(P>0.05)。结论对子宫内膜息肉采用宫腔镜联合屈螺酮炔雌醇治疗的临床疗效显著,可有效改善患者月经情况,大大降低子宫内膜息肉复发率,减少不良反应发生率,值得临床推广与应用。
Objective To investigate the clinical effect of hysteroscopy combined with drospirenone ethinyl estradiol on endometrial polyps. Methods 91 cases of endometrial polyps patients were randomly divided into observation group (46 cases) and control group (45 cases). Patients in the control group received other treatments after surgery, and patients in the observation group started taking drospirenone ethinyl estradiol on the day after the operation. After 6 months of treatment, the results of follow-up examination in two groups were observed to find out the recurrence of endometrial polyps. Results After treatment, the relapse rate was 4.3% in 2 cases in the observation group and in the control group, the recurrence rate was 17.8% in 8 cases and the recurrence rate in the observation group was significantly lower than that in the control group (P <0.05). The observation group 45 cases of menstruation returned to normal, accounting for 97.8% (45/46); 35 cases of the control group menstruation returned to normal, accounting for 77.8% (35/45), the observation group menstrual recovery was significantly higher than the control group (P <0.05 ). The observation group had 4 cases of headache nausea, accounting for 8.7% (4/46), 3 cases of mood swings, accounting for 6.5% (3/46), 2 cases of menstrual bleeding, accounting for 4.3% (2/46) and adverse reactions (N = 19.6%, 9/46). There were 0 cases of headache nausea in the control group, 4 cases of mood swings, accounting for 8.9% (4/45), 4 cases of menstrual bleeding (8.9%, 4/45), adverse reactions Was 17.8% (8/45). There was no significant difference in the incidence of adverse reactions between the two groups (P> 0.05). Conclusion Endometrial polyps using hysteroscopy combined with drospirenone ethinyl estradiol treatment of significant clinical efficacy, which can effectively improve the patient’s menstrual conditions, greatly reduce the recurrence rate of endometrial polyps and reduce the incidence of adverse reactions, is worthy of clinical promotion and application .